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StatPearls Week 3: Mental Status Exam, Psychopharmacology & DSM-5-TR

📄 42 questions 🩹 OCD · Substance Use · Autism · Serotonin Syndrome 🎓 PMHNP Clinical Practice
OCD & Tic Disorders Psychopharmacology DSM-5-TR Criteria Substance Use Disorders Autism Spectrum Serotonin Syndrome Clozapine Monitoring Child & Adolescent Psych
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42 clinical practice questions — click each to reveal answers and explanations
Q1
A 17-year-old female presents with severe abdominal pain with physical findings indicative of acute appendicitis. She insists on washing her hands every hour, which interferes with clinical care. Attempts to prioritize diagnostic procedures over her hand-washing routine result in increased patient anxiety. What is the most appropriate approach to manage the patient's compulsive behavior? A. Explain the need for imaging to confirm the diagnosis. B. Set a limit to restrict hand washing to 10 times. C. Make time for the patient to complete handwashing. D. Explain the risks of frequent hand washing.
Q2
A 2-year-old patient carries a blanket at all times. Her mother fears she will remain attached forever. Developmental assessment is unremarkable. What should be advised? A. Yes, it is important at age 2 to get rid of it. B. Children should gradually be weaned from their favorite toy. C. This normal attachment may last throughout the preschool years. D. Try to reason with the child that this habit needs to be broken.
Q3
A 17-year-old girl with a strong family history of bipolar disorder is admitted for lack of sleep for 4 days with high energy, rapid speech, and grandiosity. She is started on valproic acid. Two days later, psychiatric symptoms worsen and she reports severe abdominal pain and tingling. What is the appropriate next step? A. Request GI evaluation and stop valproic acid. B. Request medical evaluation and stop valproic acid. C. Request neurological evaluation and prescribe morphine. D. Request substance use evaluation and prescribe morphine.
Q4
A 9-year-old boy presents with poor school performance and disruptive behaviors. He enjoys numbers but dislikes reading and writing. He received speech therapy for language delay. What is the best next step? A. ADHD treatment. B. Academic accommodations. C. Psychometric testing. D. Psychotherapy.
Q5
A 9-year-old boy with poor school performance, disruptive behaviors, speech therapy history for language delay, and preference for numbers over reading. What is the best next step? A. ADHD treatment. B. Academic accommodations. C. Psychometric testing. D. Psychotherapy.
Q6
A 17-year-old boy with major depressive disorder is prescribed fluoxetine. His mother calls the clinic asking for information about his diagnosis, saying she wants to take better care of him. What is the most appropriate response? A. Cannot confirm or deny he is a patient. B. Provide the diagnosis as she is his mother. C. Encourage the mother to come to the next visit with her son. D. Ask the mother to hand him the phone to obtain his permission.
Q7
Same 17-year-old boy scenario. Mother calls asking about her son's diagnosis. What is the most appropriate response? A. Cannot confirm or deny he is a patient. B. Provide the diagnosis as she is his mother. C. Encourage the mother to come to the next clinic visit with her son. D. Ask the mother to hand him the phone.
Q8
A 55-year-old woman with a 30-pack-year smoking history stopped smoking for 2 months after gathering information about cessation. Based on the Transtheoretical Model (TTM), what is the most appropriate action plan? A. Recognize triggers that may lead to relapse and develop an action plan. B. No additional action — she is in the maintenance stage. C. Any talk therapy for conscious-raising. D. Further information gathering.
Q9
A patient with schizophrenia compliant for 5 years is moving 4 hours away. The provider refers to a new specialist, prescribes medication to last until the next appointment, and arranges medical records transfer while remaining available by phone. This demonstrates which understanding? A. How to avoid patient abandonment. B. Termination is unilateral. C. Patient has autonomy over seeing the new provider. D. Appropriate medication prescribing.
Q10
A 9-year-old boy repeats everything said to him (echolalia), jerks his head, grimaces, and shrugs his shoulders. These symptoms started a year ago and worsened. Which disorder is associated with his condition? A. Schizoaffective disorder. B. Obsessive-compulsive disorder. C. Psychotic disorder. D. Autism.
Q11
A 17-year-old girl with trichotillomania (hair pulling disorder) with no improvement. No prior therapy or psychiatric medication. What is the best initial management? A. SSRIs. B. Behavior modification. C. Topical corticosteroids. D. Avoiding traction hairstyles.
Q12
A 37-year-old man with schizophrenia has worsening hallucinations, incoherence, and suicidal ideation on risperidone. He could not tolerate haloperidol or olanzapine. The clinician will switch antipsychotics. Which patient factor most affects the choice? A. Baseline LDL/HDL/triglycerides. B. Baseline absolute neutrophil count. C. Baseline fasting blood glucose. D. Baseline BMI.
Q13
A 30-year-old man has panic attacks while flying, with anticipatory anxiety. He prefers trains but they are too time-consuming. What is the first-line therapy? A. CBT. B. Reassurance and follow-up. C. SSRI. D. Benzodiazepines.
Q14
A chronically ill, bed-bound 78-year-old man with diabetes and stroke presents with severe malnutrition, altered mental status, facial bruising, skull fracture, and subdural hematoma. He lives with his son and daughter-in-law. What is the next step? A. Wait for investigator before treating. B. Obtain consent from power of attorney before involving investigators. C. Report suspected abuse to authorities. D. Perform further testing to rule out organic cause before involving others.
Q15
A 19-year-old woman with alcohol use disorder has had several relapses. She appears withdrawn; her father is upset. Which statement by her father would be most appropriate to support? A. Support group and medication only. B. Combination of medication, peer support, and close monitoring. C. A peer recovery coach only. D. Frequent testing with severe repercussions.
Q16
An 18-month-old girl has daily temper tantrums, sensitivity to the vacuum cleaner, no eye contact, and unusual repetitive finger movements near her eyes. Parents are concerned about hearing and vision. What is the best next step? A. Screen for autism spectrum disorder. B. Obtain a lead level. C. Enroll in parent management training. D. Prescribe hydroxyzine.
Q17
A 46-year-old man with severe opioid use disorder completed medically supervised withdrawal 5 days ago. His wife objects to methadone/buprenorphine, saying 'that's just trading one addiction for another.' What is the most appropriate response? A. Methadone or buprenorphine cuts overdose mortality by more than 50% and allows patients to work and care for their families. B. Successful withdrawal suggests MOUD may not be necessary. C. These medications treat dependence by increasing dopamine and decreasing GABA. D. A brief MOUD course reduces relapse risk by 63%.
Q18
An 8-year-old child has frequent random outbursts of obscenities at school and home, worse when tired or frustrated. What is the most likely prognosis? A. Temporary, will resolve within 1 year. B. Will worsen for 1 year then resolve. C. Will likely resolve with an IEP or 504 plan. D. No risk of school performance impairment.
Q19
A 32-year-old woman with major depressive disorder on citalopram 40 mg daily for 1.5 years is being switched to tranylcypromine (MAOI). She is instructed to wait 14 days after stopping citalopram. What adverse effect does this washout period prevent? A. Hypertensive crisis. B. Serotonin syndrome. C. Suicidal ideation. D. Orthostatic hypotension.
Q20
A 16-year-old boy with ADHD and MDD presents with new suicidal ideation and worsening symptoms 10 days after starting a new medication. Which medication was most likely prescribed? A. Lurasidone. B. Escitalopram. C. Trazodone. D. Risperidone.
Q21
A 20-month-old boy has temper tantrums, sensory sensitivity to loud noises, aggression when asked to participate, inability to line up, fleeting eye contact, no pointing, no meaningful words, and does not respond to his name. Normal hearing evaluation. What is the best initial management? A. Twice-monthly ABA therapy. B. Refer to early intervention and seek an individualized family service plan. C. MRI brain. D. Electroencephalogram.
Q22
A 17-year-old boy ingested his roommate's entire bottle of antidepressant. ECG shows polymorphic ventricular tachycardia (torsades de pointes). The antidepressant can cause hyponatremia. Which is the most appropriate immediate treatment? A. Activated charcoal. B. Digoxin. C. Magnesium sulfate. D. IV fluid bolus.
Q23
A 40-year-old woman with chronic depression unresponsive to paroxetine and sertraline presents with social anxiety, possible past trauma, and wishes she didn't have to live as herself. The MMPI is recommended at the next appointment. What is the MMPI most likely assessing? A. Unresolved past trauma affecting relationships. B. Wide scope of symptoms to arrive at a diagnosis. C. Predisposition for loneliness and isolation. D. Red flags for impending suicide attempt.
Q24
A 3-year-old boy has difficulty speaking, cannot speak in complete sentences, does not respond to his name at times, normal milestones on previous encounters, and clinician suspects a language disorder. What is the next best step? A. Karyotyping. B. Reassurance. C. Hearing assessment. D. Intelligence testing.
Q25
A 60-year-old man with previous manic episodes and depression, poor response to lithium and valproate, is prescribed another antiepileptic and improves within a week but then develops nausea, dizziness, fatigue, and lethargy. What is the most likely cause? A. Hyponatremia. B. Hypocalcemia. C. Hypernatremia. D. Hypomagnesemia.
Q26
A 39-year-old man with opioid use disorder wants to enroll in an opioid rehabilitation center. The provider plans a medication with a long half-life causing less euphoria. Before starting, the clinician should: A. Recheck medical history with PCP. B. Review prescription drug monitoring data. C. Obtain a clean urine drug screen. D. Obtain a verbal contract for follow-ups.
Q27
A 15-year-old emancipated boy who was physically abused by his alcoholic father, has moved frequently, was detained for minor theft, but is doing well in school, elected class president, and has money saved for college. He regularly called his maternal uncle in times of trouble. What primarily enabled his recovery? A. Father's military background. B. Maternal uncle's availability. C. Detainment as a minor. D. Emancipation.
Q28
A 32-year-old man developed labile moods, pressured speech, reckless driving, and missing work after a motor vehicle accident 6 months ago. Which brain area is most likely affected? A. Occipital lobe. B. Temporal lobe. C. Frontal lobe. D. Parietal lobe.
Q29
A 32-year-old man with trigeminal neuralgia and bipolar disorder I started a medication that auto-induces its metabolism 2 weeks ago and developed a rash and fatigue. Which test will reveal the cause? A. Blood culture. B. Basic metabolic panel. C. Complete blood count. D. Thyroid function tests.
Q30
A 42-year-old patient presents with hypertension, tachycardia, tremors, akathisia, agitation, hyperthermia, increased bowel sounds, dilated pupils, and hyperreflexia. What is the possible antidote? A. Bromocriptine. B. Propranolol. C. Dantrolene. D. Cyproheptadine.
Q31
Which laboratory tests must be monitored during the first four weeks of clozapine therapy? A. Fasting blood glucose and troponin. B. Uric acid and eosinophil count. C. Troponin and baseline EKG. D. CRP and fasting blood glucose.
Q32
A 16-year-old girl was raped by her stepfather 4 days ago. She now describes 4 previous adverse childhood experiences (ACEs). What is she most at increased risk for? A. Acute HIV infection. B. Promiscuity in the future. C. Chronic health conditions. D. No increased risk.
Q33
A diet plan is being made for a 17-year-old girl with an eating disorder. Which short-term goal is appropriate? A. Weight within acceptable range. B. Eating a well-balanced meal. C. Looking at the mirror daily. D. Resolving family disagreements based on weight.
Q34
A 54-year-old man taking medication for alcohol use disorder recalls that if he drinks alcohol, his face flushes, heart races, and he becomes sweaty and nauseous. What enzyme does this medication inhibit? A. CYP2E1. B. Alcohol dehydrogenase. C. Aldehyde dehydrogenase. D. Catalase.
Q35
A 55-year-old man is hospitalized for suicidal ideation with a loaded gun. Family history of depression and suicide. Started on fluoxetine and discharged after 2 weeks. His wife later reports episodes of high energy and productivity with only 3-4 hours of sleep. Four weeks later he is readmitted after a suicide attempt. What most likely occurred? A. Medication error. B. Communication error. C. Treatment error. D. Diagnostic error.
Q36
A 31-year-old man with treatment-resistant schizophrenia on clozapine 300 mg twice daily is hospitalized and remains tobacco-free. On day 3, clozapine level is 1296 μg/L (therapeutic: 250-550). He has a generalized tonic-clonic seizure. What would most likely have prevented this? A. Decreasing the clozapine dose. B. Scheduled benzodiazepines. C. Starting nicotine-replacement therapy. D. Prophylactic topiramate.
Q37
A 40-year-old patient with opioid use disorder is considering a methadone maintenance program. Which statement is most accurate? A. MMPs aim to eliminate opioid use and are most effective under 1 year. B. MMPs are effective but have significant negative impacts on social/occupational functioning. C. MMPs provide long-term stabilization, reduce illicit opioid use, improve social functioning, and decrease infectious disease risk. D. MMPs focus only on medication and do not incorporate counseling.
Q38
Which screening tool is most sensitive for detecting alcohol use disorder in the general population? A. CAGE. B. T-ACE. C. AUDIT. D. SMAST-G.
Q39
Which aspect is most critical when screening for substance use disorder? A. Frequency and quantity of substance use. B. Family history of SUDs. C. Physical signs and symptoms. D. Patient's readiness to change.
Q40
Which is the most accurate statement about peer support for patients with stimulant use disorder? A. Peer support is ineffective for linkage to care. B. Peer navigators should only be used in inpatient settings. C. Peer navigators may be considered to help link patients to assessment and treatment, although evidence is limited. D. Peer support is the most effective intervention and should be prioritized over all other strategies.
Q41
A 35-year-old man presents with agitation, increased heart rate, and elevated blood pressure after using methamphetamine for several months. What is the most appropriate initial step? A. Immediate tapering schedule for methamphetamine. B. Provide supportive care and monitor for cardiovascular complications. C. Administer a benzodiazepine. D. Short-term antipsychotic medication.
Q42
An 82-year-old man with Alzheimer disease is admitted for pneumonia. On day 3, he becomes withdrawn, minimally responsive, and sleepy. He was alert and conversational the day before (per his sister). CAM exam is difficult with poor attention. His respiratory and heart rates are increased and he requires more oxygen. What is the most likely diagnosis? A. Progression of Alzheimer disease. B. Hypoactive delirium. C. Major depressive disorder. D. Sundowning syndrome.
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